Correction to my earlier post, I double checked everything and somehow installed the wrong SkyX daily build.
Using the following software version and all now seems to be working here
The SkyX version 10.5.0 (Build 11360)
Windows 10 Version 1709 Build 16299.192 fully patched
PHD2 Version 2.6.4 dev7
I still have the COM changes in place as per Bob Denny’s work around, not sure if that makes a difference.
The only WIndows update that reinstalled was KB4056892